Swimming Lien Hughes in As the World Turns, she was the 1st Asian-Western to exist as the regular in the daytime soap opera. Her virtually all large role can be when Dr. Deb Chen in ER. Ming-Na appeared in the pic version of Amy Tan's novel The Joy Luck Club and played Chun-Li in Street Fighter. She besides appeared around the supporting role on the comedy series The Single Guy which starred Jonathan Silverman.

Ming-Na besides provided a voice for the title character in Disney's animated moving-picture show Mulan, Aki Ross in the computer animated film Final Fantasy: The Spirits Within, and Detective Ellen Yin in the animated series The Batman.

Within Fall 2005, she starred on the NBC television series Inconceivable as the lead character, Rachel Lu.